“Cancer Biology” Science-Research, February 2022 — summary from Europe PMC
Europe PMC — summary generated by Brevi Assistant
Background: Prostate cancer is a common cancer in elderly guys with the first boosting new cases and the second leading reason for cancer fatality, but the molecular mechanisms underlying the pathogenesis of prostate cancer stay unclear. Cell biology experiments demonstrated that FERMT2 prevented tumor cell spreading and migration. Verdict: Our findings revel that downregulation of FERMT2 and the focal bond path are the main characteristics of PCa and FERMT2 could be the possible biomarker or treatment target for PCa. MicroRNAs are little non-coding RNAs that manage genetic expression at the post-transcriptional degree. Aberrant expression of miR-381 in blood examples indicates that it can be made use of as a diagnostic marker in cancer. This review adequately sums up the impact of miR-381 on tumour organic practices, in addition to the professional application possibility of miR-381 for the treatment of cancer. We have developed significant expertise in researching the duty of platelets in cancer biology. Coevolutionary adjustments have also happened in vertebrate infections and their vertebrate hosts that show their particular evolutionary communications. Platelets also generate flowing microvesicles that enhance membrane surface-area experiences and mark viral targets. With sunitinib treatment of metastatic kidney cell cancer, most patients finish up creating resistance in time. We created an in vivo xenograft tumor model and contrasted tumor growth rate, morphological, and transcriptomic differences between alternative and conventional treatment timetables. More examination of the signaling paths underlying these morphological modifications might lead to potential therapeutic targets to be used in a combined therapy with sunitinib, which uses promise in postponing/reversing the resistance of sunitinib.
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- https://europepmc.org/article/PPR/PPR439043 — Identification of the Dysregulated Pathways and Key Gene in Prostate Cancer by Transcriptome Analysis and Cell Biology Experiments.
- https://europepmc.org/article/MED/35014178 — MicroRNA-381 in human cancer: Its involvement in tumour biology and clinical applications potential.
- https://europepmc.org/article/MED/35022962 — Of vascular defense, hemostasis, cancer, and platelet biology: an evolutionary perspective.
- https://europepmc.org/article/MED/35054064 — The Impact of Modifying Sunitinib Treatment Scheduling on Renal Cancer Tumor Biology and Resistance.
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