“Functional Genomics” Science-Research, December 2021, Week 4 — summary from NCBI Gene
NCBI Gene — summary generated by Brevi Assistant
13 is a tetrameric glycolytic enzyme that catalyzes the relatively easy to fix conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. There is a high level of homology between aldolase A and C. Defects in ALDOB create hereditary fructose intolerance. This gene inscribes a protein which communicates with the N-terminal area of BRCA1. The BARD1/BRCA1 communication is disrupted by tumorigenic amino acid alternatives in BRCA1, indicating that the formation of a secure complex between these proteins might be an essential aspect of BRCA1 tumor reductions. This gene encodes a participant of the epidermal development factor EGF receptor family of receptor tyrosine kinases. Allelic variations at amino acid placements 654 and 655 of isoform a positions 624 and 625 of isoform b have been reported, with one of the most typical allele, Ile654/Ile655, shown below. The Lewis histo-blood group system consists of a collection of fucosylated glycosphingolipids that are manufactured by exocrine epithelial cells and distributed in body fluids. This gene is a member of the fucosyltransferase family, which militarizes the enhancement of fucose to forerunner polysaccharides in the last action of Lewis antigen biosynthesis. This gene encodes a lump suppressor protein including transcriptional activation, DNA binding, and oligomerization domains. Extra isoforms have also been revealed to result from making use of alternate translation initiation codons from identical records variations PMIDs: 12032546 20937277.
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