“Functional Genomics” Science-Research, September 2021, Week 4 — summary from NCBI Gene
NCBI Gene — summary generated by Brevi Assistant
13 is a tetrameric glycolytic enzyme that militarizes the relatively easy to fix conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. There is a high degree of homology between aldolase A and C. Defects in ALDOB cause hereditary fructose intolerance. This gene inscribes a protein which communicates with the N-terminal region of BRCA1. The BARD1/BRCA1 interaction is interfered with by tumorigenic amino acid substitutions in BRCA1, implying that the development of a secure facility between these proteins may be an essential aspect of BRCA1 lump suppression. This gene encodes a participant of the skin growth element EGF receptor family of receptor tyrosine kinases. Allelic variants at amino acid positions 654 and 655 of isoform a settings 624 and 625 of isoform b have been reported, with the most common allele, Ile654/Ile655, revealed right here. The Lewis histo-blood team system comprises a collection of fucosylated glycosphingolipids that are manufactured by exocrine epithelial cells and flow in body fluids. This gene is a member of the fucosyltransferase family, which militarizes the enhancement of fucose to forerunner polysaccharides in the last action of Lewis antigen biosynthesis. This gene inscribes a lump suppressor healthy protein having transcriptional activation, DNA binding, and oligomerization domains. Added isoforms have additionally been revealed to arise from making use of alternate translation initiation codons from identical records variants PMIDs: 12032546 20937277.
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